Publications by Year: 2017

Jiang K, Wang H, Cai W-B, Wang H. Li Electrochemical Tuning of Metal Oxide for Highly Selective CO2 Reduction [Internet]. ACS Nano 2017;(DOI: 10.1021) Publisher's Version acsnano2e7b03029.pdf
Liang F, Guo Y, Hou S, Quan Q. Photonic-plasmonic hybrid single-molecule nano sensor measures the effect of fluorescent labels on DNA-protein dynamics [Internet]. Sciences Advances 2017;3(5) Publisher's Version
Hou S, Guo Y, Tang Y, Quan Q. Synthesis and Stabilization of Colloidal Perovskite Nanocrystals by Multidentate Polymer Micelles [Internet]. ACS Applied Materials & Interfaces 2017; Publisher's Version
Novakova E, Woodhams DC, Rodriguez-Ruano SM, Brucker RM, Leff JW, Maharaj A, Knight R, Scott J. Mosquito Microbiome Dynamics, a Background for Prevalence and Seasonality of West Nile Virus. [Internet]. Frontiers in Microbiology 2017;(1664-302X) Publisher's Version 227863_woodhams_provisionalpdf.pdf
Saulsberry A, Pinchas M, Noll A, Lynch JA, Bordenstein SR, Brucker RM. Establishment of F1 hybrid mortality in real time. BMC Evolutionary Biology 2017;17.1
Brooks AW, Kohl KD, Brucker RM, van Opstal EJ, Bordenstein SR. Phylosymbiosis: Relationships and Functional Effects of Microbial Communities across Host Evolutionary History. PLOS Biology 2017;15.1(e1002587):1-29. journal.pbio_.2000225.pdf
Ouyang M, Hill W, Lee JH, Hur SC. Microscale Symmetrical Electroporator Array as a Versatile Molecular Delivery System [Internet]. Scientific Reports 2017;7:11. Publisher's VersionAbstract

Successful developments of new therapeutic strategies often rely on the ability to deliver exogenous molecules into cytosol. We have developed a versatile on-chip vortex-assisted electroporation system, engineered to conduct sequential intracellular delivery of multiple molecules into various cell types at low voltage in a dosage-controlled manner. Micro-patterned planar electrodes permit substantial reduction in operational voltages and seamless integration with an existing microfluidic technology. Equipped with real-time process visualization functionality, the system enables on-chip optimization of electroporation parameters for cells with varying properties. Moreover, the system’s dosage control and multi-molecular delivery capabilities facilitate intracellular delivery of various molecules as a single agent or in combination and its utility in biological research has been demonstrated by conducting RNA interference assays. We envision the system to be a powerful tool, aiding a wide range of applications, requiring single-cell level co-administrations of multiple molecules with controlled dosages.