Scalable nanobeam photonic sensors for high sensitivity protein detection

Citation:

Liang F, Clarke NA, Patel R, Loncar M, Quan Q. Scalable nanobeam photonic sensors for high sensitivity protein detection [Internet]. Optics Express 2013;21:32306.
oe-21-26-32306.pdf1.12 MB

Abstract:

Scalable microfabrication technology has enabled semiconductor and microelectronics industries, among other fields. Meanwhile, rapid and sensitive bio-molecule detection is increasingly important for drug discovery and biomedical diagnostics. In this work, we designed and demonstrated that photonic crystal sensor chips have high sensitivity for protein detection and can be mass-produced with scalable deep-UV lithography. We demonstrated label-free detection of carcinoembryonic antigen from pg/mL to μg/mL, with high quality factor photonic crystal nanobeam cavities.

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Last updated on 10/30/2015