Binary DNA nanostructures for data encryption.


Halvorsen K, Wong WP. Binary DNA nanostructures for data encryption. PLoS One 2012;7(9):e44212.
2012_halvorsen_plos.pdf488 KB

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We present a simple and secure system for encrypting and decrypting information using DNA self-assembly. Binary data is encoded in the geometry of DNA nanostructures with two distinct conformations. Removing or leaving out a single component reduces these structures to an encrypted solution of ssDNA, whereas adding back this missing "decryption key" causes the spontaneous formation of the message through self-assembly, enabling rapid read out via gel electrophoresis. Applications include authentication, secure messaging, and barcoding.

Last updated on 06/23/2016