Binary DNA nanostructures for data encryption.

Citation:

Halvorsen K, Wong WP. Binary DNA nanostructures for data encryption. . PLoS One 2012;7(9):e44212.

Abstract:

We present a simple and secure system for encrypting and decrypting information using DNA self-assembly. Binary data is encoded in the geometry of DNA nanostructures with two distinct conformations. Removing or leaving out a single component reduces these structures to an encrypted solution of ssDNA, whereas adding back this missing "decryption key" causes the spontaneous formation of the message through self-assembly, enabling rapid read out via gel electrophoresis. Applications include authentication, secure messaging, and barcoding.